Amy Clewell, ND, Senior Research Associate
Dr. Amy Clewell is Senior Research Associate for AIBMR Life Sciences, Inc..
Dr. Clewell earned a bachelor’s of science degree in Biology from Indiana University in Bloomington, Indiana, and a doctoral degree in Naturopathic Medicine from Bastyr University in Kenmore, Washington.
Besides post-graduate clinical experience as a licensed naturopathic physician, Dr. Clewell’s work in research began as a student and laboratory technician at Indiana University where she worked with Dr. Thomas Donahue for three years in the area of translational initiation using S. cerevisiae as a model system. She continued her research pursuits for another five years as a research technician and laboratory manager working in Dr. Karla Kirkegaard’s laboratory at both the University of Colorado and Stanford University. Her focus there was on the biochemistry of polio and hepatitis C virus propagation using an S. cerevisiae model.
Dr. Clewell pursued a doctorate in naturopathic medicine at Bastyr University, and graduated in 2004. While attending Bastyr University, she remained active in research, participating in various capacities with research projects at Bastyr University and the University of Washington.
Dr. Clewell is a licensed naturopathic physician in the state of Washington, and her clinical experiences have included patient care at Vashon Natural Medicine and London Health Center, both located in Washington State. As a physician, she strives to integrate complementary and alternative medicine with standard medical care in the prevention and treatment of disease and the optimization of health. She individualizes treatments through the use of nutrition, targeted nutrients and botanicals, lifestyle counseling and physical medicine. She is the current president of the Indiana Association of Naturopathic Physicians (INANP), and is also a current member of the American Association of Naturopathic Physicians (AANP). She is a full member of the Society of Toxicology (SOT).
At AIBMR Life Sciences, Dr. Clewell is a Senior Research Associate, where she specializes in evaluating and compiling scientific research on natural ingredient safety and efficacy, dietary supplement formulations, responding to regulatory compliance inquiries, writing technical reports and scholarly manuscripts for peer-reviewed journal publications and trade journals, the design and interpretation of laboratory and clinical studies, preparing generally recognized as safe (GRAS) self-determinations, FDA notifications, and FDA New Dietary Ingredient notifications, and performing due diligence reviews. She also serves as a reviewer for several scientific journals. She currently manages research projects for all of AIBMR Life Sciences offices.
Publications:
Clewell A, Barnes M, Endres JR, Ahmed M, Ghambeer DK. Efficacy and Tolerability Assessment of a Topical Formulation Containing Copper Sulfate and Hypericum perforatum on Patients With Herpes Skin Lesions: A Comparative, Randomized Controlled Trial. J Drugs Dermatol. 2012 Feb 1;11(2):209-15. PubMed PMID: 22270204.
Schauss A, Endres J, Clewell A. Chapter 2: Safety of Unsaturated Vitamin E Tocotrienols and Their Isomers. Tocotrienols: Vitamin E Beyond Tocopherols, Second Edition. CRC Press (Taylor and Francis Group) 2012.
Schauss A, Stenehjem J, Park J, Endres J, Clewell A. Chapter 2: Effect of the
Novel Low Molecular WEgith Hydrolyzed Chicken Sternal Cartilage Extract, BioCell
Collagen, on Improving Osteoarthrities-Related Symptoms: A Randomized, Double-Blind,
Placebo-Controlled Trial. J Agric Food Chem. 2012 Apr 25:60(16):4096-101. Epub
2012 Apr 16. PubMed PMID:22486722.
Ruff KJ, Endres JR, Clewell AE, Szabo JR, Schauss AG. Safety evaluation of a natural eggshell membrane-derived product. Food Chem Toxicol. 2012 Jan 3;50(3-4):604-611. [Epub ahead of print] PubMed PMID: 22245377. Schauss AG, Glavits R, Endres J, Jensen GS, Clewell A. Safety Evaluation of a Proprietary Food-Grade, Dried Fermentate Preparation of Saccharomyces cerevisiae. Int J Toxicol. 2012 Jan;31(1):34-45. Epub 2012 Jan 5. PubMed PMID: 22222580.
Endres J, Qureshi I, Clewell A, Schauss A. Chapter 8: Culinary Spices in
Cancer Chemoprevention. Bioactive Foods and Extracts, Cancer Treatment
and Prevention. CRC Press (Taylor and Francis Group) 2011.
Endres J, Clewell A, Barnes M. Natural concerns: testing products for quality,
safety, and efficacy. Nutritional Outlook, 2011 14:62-66.
Schauss AG, Vértesi A, Endres JR, Hirka G, Clewell A, Qureshi I, Pasics I.
Evaluation of the safety of the dietary antioxidant ergothioneine using the
bacterial reverse mutation assay. Toxicology. 2010 Jul 30. [Epub ahead of print]
PubMed PMID: 20674647.
Schauss AG, Clewell A, Balogh L, Szakonyi IP, Financsek I, Horváth J, Thuroczy
J, Beres E, Vertesi A, Hirka G. Safety evaluation of an açai-fortified fruit and
berry functional juice beverage (Monavie Active(R)). Toxicology. 2010 May 7.
PubMed PMID: 20452390.
Clewell A, Qureshi I, Endres J, Horváth J, Financsek I, Neal-Kababick J, Jade
K, Schauss AG. Toxicological Evaluation of a Dietary Supplement Formulated for
Male Sexual Health Prior to Market Release. Regul Toxicol Pharmacol. 2009 Dec 28.
PubMed PMID: 20043970.
Farber TM, Clewell AE, Endres JR, Hauswirth J, Van Gemert M, Schauss AG,
Sheane CA. Safety assessment of a novel ingredient for removable chewing gum.
Food Chem Toxicol. 2009 Dec 24. PubMed PMID: 20035819.
Schauss AG, Somfai-Relle S, Financsek I, Glavits R, Parent SC, Endres JR,
Varga T, Szücs Z, Clewell A. Single- and repeated-dose oral toxicity studies of
citicoline free-base (choline cytidine 5'-pyrophosphate) in Sprague-Dawley rats.
Int J Toxicol. 2009 Nov-Dec;28(6):479-87. PubMed PMID: 19966140.
Endres JR, Clewell A, Jade KA, Farber T, Hauswirth J, Schauss AG. Safety
assessment of a proprietary preparation of a novel Probiotic, Bacillus coagulans,
as a food ingredient. Food Chem Toxicol. 2009 Jun;47(6):1231-8. Epub 2009 Feb 25.
PubMed PMID: 19248815; PubMed Central PMCID: PMC2726964.
Lyle JM, Clewell A, Richmond K, Richards OC, Hope DA, Schultz SC, Kirkegaard
K. Similar structural basis for membrane localization and protein priming by an
RNA-dependent RNA polymerase. J Biol Chem. 2002 May 3;277(18):16324-31. Epub 2002
Feb 27. PubMed PMID: 11877407.
Zhao XJ, Raitt D, V Burke P, Clewell AS, Kwast KE, Poyton RO. Function and
expression of flavohemoglobin in Saccharomyces cerevisiae. Evidence for a role in
the oxidative stress response. J Biol Chem. 1996 Oct 11;271(41):25131-8. PubMed
PMID: 8810268.