Amy Clewell, ND, Senior Research Associate
Dr. Amy Clewell is a Senior Research Associate at AIBMR Life Sciences. Dr. Clewell earned a Bachelor of Science degree in biology from Indiana University in Bloomington, Indiana and a doctoral degree in Naturopathic Medicine from Bastyr University in Kenmore, Washington. In addition to clinical experience as a licensed naturopathic physician, Dr. Clewell has extensive research experience. Her work in research began as a student and laboratory technician at Indiana University where she spent three years working with Dr. Thomas Donahue in the area of translational initiation using Saccharomyces cerevisiae as a model system. She continued her research pursuits for another five years as a research technician and laboratory manager in Dr. Karla Kirkegaard’s laboratories at both the University of Colorado and Stanford University, studying the biochemistry of polio and hepatitis C virus propagation using an S. cerevisiae model.
While attending Bastyr University for her doctoral degree, she remained active in research by designing and implementing a retrospective chart analysis at the Bastyr Center for Natural Health, co-founding a student research club, and participating in various capacities on other research projects at Bastyr University and the University of Washington. She also served as co-chair of the Site Committee for the Alternative Health Care Access Campaign, providing alternative health care to low income and homeless residents of Seattle.
At AIBMR Life Sciences, Dr. Clewell specializes in evaluating and compiling scientific research on the safety and efficacy of dietary supplement and food ingredients, as well as regulatory compliance related to these industries. She is an author on numerous scholarly manuscripts for peer–reviewed journal publications and trade journals, especially related to the safety of ingredients, and has also served as a peer-reviewer for several toxicologically-focused journals. She has been intimately involved in the preparation of generally recognized as safe (GRAS) self-determination dossiers, as well as GRAS and New Dietary Ingredient (NDI) notifications sent to FDA. She has served on numerous GRAS self-determination expert panels, and is currently a full member of the Society of Toxicology. She is closely involved in the management of projects at AIBMR Life Sciences.
Dr. Clewell is a licensed naturopathic physician in the State of Washington and her clinical experiences include patient care in several capacities in Washington State. She is the current president of the Indiana Association of Naturopathic Physicians and a current member of the American Association of Naturopathic Physicians.
Odendaal A, Deshmukh N, Marx T, Schauss A, Endres J, Clewell A. Safety
Assessment of a Hydroethanolic Extract of Caralluma fimbriata.
2013 Jun 14 [Epub ahead of print]. PubMed PMID: 23771637.
Marx T, Clewell A, Barnes M. Chapter 40. Metabolic syndrome: diet, obesity,
and chronic inflammation. Bioactive food as dietary interventions for diabetes.
Watson and Preedy: 2013. 503-517.
Clewell A, Barnes M, Endres JR, Ahmed M, Ghambeer DK. Efficacy and Tolerability Assessment of a Topical Formulation Containing Copper Sulfate and Hypericum perforatum on Patients With Herpes Skin Lesions: A Comparative, Randomized Controlled Trial. J Drugs Dermatol. 2012 Feb 1;11(2):209-15. PubMed PMID: 22270204.
Schauss A, Endres J, Clewell A. Chapter 2: Safety of Unsaturated Vitamin E Tocotrienols and Their Isomers. Tocotrienols: Vitamin E Beyond Tocopherols, Second Edition. CRC Press (Taylor and Francis Group) 2012.
Schauss A, Stenehjem J, Park J, Endres J, Clewell A. Chapter 2: Effect of the
Novel Low Molecular WEgith Hydrolyzed Chicken Sternal Cartilage Extract, BioCell
Collagen, on Improving Osteoarthrities-Related Symptoms: A Randomized, Double-Blind,
Placebo-Controlled Trial. J Agric Food Chem. 2012 Apr 25:60(16):4096-101. Epub
2012 Apr 16. PubMed PMID:22486722.
Ruff KJ, Endres JR, Clewell AE, Szabo JR, Schauss AG. Safety evaluation of a natural eggshell membrane-derived product. Food Chem Toxicol. 2012 Jan 3;50(3-4):604-611. [Epub ahead of print] PubMed PMID: 22245377. Schauss AG, Glavits R, Endres J, Jensen GS, Clewell A. Safety Evaluation of a Proprietary Food-Grade, Dried Fermentate Preparation of Saccharomyces cerevisiae. Int J Toxicol. 2012 Jan;31(1):34-45. Epub 2012 Jan 5. PubMed PMID: 22222580.
Endres J, Qureshi I, Clewell A, Schauss A. Chapter 8: Culinary Spices in
Cancer Chemoprevention. Bioactive Foods and Extracts, Cancer Treatment
and Prevention. CRC Press (Taylor and Francis Group) 2011.
Endres J, Clewell A, Barnes M. Natural concerns: testing products for quality,
safety, and efficacy. Nutritional Outlook, 2011 14:62-66.
Schauss AG, Vértesi A, Endres JR, Hirka G, Clewell A, Qureshi I, Pasics I.
Evaluation of the safety of the dietary antioxidant ergothioneine using the
bacterial reverse mutation assay. Toxicology. 2010 Jul 30. [Epub ahead of print]
PubMed PMID: 20674647.
Schauss AG, Clewell A, Balogh L, Szakonyi IP, Financsek I, Horváth J, Thuroczy
J, Beres E, Vertesi A, Hirka G. Safety evaluation of an açai-fortified fruit and
berry functional juice beverage (Monavie Active(R)). Toxicology. 2010 May 7.
PubMed PMID: 20452390.
Clewell A, Qureshi I, Endres J, Horváth J, Financsek I, Neal-Kababick J, Jade
K, Schauss AG. Toxicological Evaluation of a Dietary Supplement Formulated for
Male Sexual Health Prior to Market Release. Regul Toxicol Pharmacol. 2009 Dec 28.
PubMed PMID: 20043970.
Farber TM, Clewell AE, Endres JR, Hauswirth J, Van Gemert M, Schauss AG,
Sheane CA. Safety assessment of a novel ingredient for removable chewing gum.
Food Chem Toxicol. 2009 Dec 24. PubMed PMID: 20035819.
Schauss AG, Somfai-Relle S, Financsek I, Glavits R, Parent SC, Endres JR,
Varga T, Szücs Z, Clewell A. Single- and repeated-dose oral toxicity studies of
citicoline free-base (choline cytidine 5'-pyrophosphate) in Sprague-Dawley rats.
Int J Toxicol. 2009 Nov-Dec;28(6):479-87. PubMed PMID: 19966140.
Endres JR, Clewell A, Jade KA, Farber T, Hauswirth J, Schauss AG. Safety
assessment of a proprietary preparation of a novel Probiotic, Bacillus coagulans,
as a food ingredient. Food Chem Toxicol. 2009 Jun;47(6):1231-8. Epub 2009 Feb 25.
PubMed PMID: 19248815; PubMed Central PMCID: PMC2726964.
Lyle JM, Clewell A, Richmond K, Richards OC, Hope DA, Schultz SC, Kirkegaard
K. Similar structural basis for membrane localization and protein priming by an
RNA-dependent RNA polymerase. J Biol Chem. 2002 May 3;277(18):16324-31. Epub 2002
Feb 27. PubMed PMID: 11877407.
Zhao XJ, Raitt D, V Burke P, Clewell AS, Kwast KE, Poyton RO. Function and
expression of flavohemoglobin in Saccharomyces cerevisiae. Evidence for a role in
the oxidative stress response. J Biol Chem. 1996 Oct 11;271(41):25131-8. PubMed